Etripamil (hydrochloride)

Etripamil (MSP-2017) hydrochloride is a short-acting, L-type calcium channel antagonist that can be used in the study of paroxysmal supraventricular tachycardia (PSVT) . Etripamil hydrochloride inhibits calcium influx through slow calcium channels, thereby slowing atrioventricular node conduction and prolonging the atrioventricular node refractory period.

Product Specifications

CAS Number

[2560549-35-9]

Product Name Alternative

MSP-2017 (hydrochloride) ; (-) -MSP-2017 (hydrochloride)

UNSPSC

12352005

Target

Calcium Channel

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

COC(C1=CC=CC(CCN(C)CCC[C@@](C#N)(C2=CC(OC)=C(C=C2)OC)C(C)C)=C1)=O.Cl

Molecular Formula

C27H37ClN2O4

Molecular Weight

489.05

References & Citations

[1]Pokorney S D, et al. CO143 Impact of Investigational, at-Home, Self-Administered, Intranasal Etripamil on the Need for Additional Medical Intervention in Patients with Supraventricular Tachycardia[J]. Value in Health, 2023, 26 (6) : S41.