Adenosine-5'-O-diphosphoribose phosphate (sodium)
Adenosine-5'-O-diphosphoribose phosphate sodium is a structural analog of NADPH. Adenosine-5'-O-diphosphoribose phosphate sodium is an HMG-CoA reductase inhibitor. Adenosine-5'-O-diphosphoribose phosphate sodium inhibits microsomal HMG-CoA reductase with an apparent Ki value of 550 μM at low thiol concentrations[1].
Product Specifications
Product Name Alternative
ADP-ribose phosphate (sodium) ; P-ADP-Rib (sodium)
UNSPSC
12352005
Target
HMG-CoA Reductase (HMGCR)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Smiles
O[C@H]1[C@@H](OP(O[Na])(O[Na])=O)[C@H](N2C=NC3=C2N=CN=C3N)O[C@@H]1COP(OP(OC[C@H]([C@H]([C@H](C=O)O)O)O)(O[Na])=O)(O[Na])=O
Molecular Formula
C15H20N5Na4O17P3
Molecular Weight
727.22
References & Citations
[1]Roitelman J, et al. Allosteric and non-allosteric forms of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase: differential inhibition of activity by adenosine 2'-monophospho-5'-diphosphoribose. J Lipid Res. 1986 Aug;27 (8) :828-35.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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