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C-Myc inhibitor 16 (iodide)

C-Myc inhibitor 16 iodide (Compound W11) is a selective c-Myc G-quadruplex (c-Myc G4) inhibitor. c-Myc inhibitor 16 iodide inhibits the transcription and translation of the c-Myc gene, disrupts the tumor cell cycle, arrests cell growth in the G0/G1 phase and activates the mitochondrial apoptosis pathway to induce early apoptosis of cancer cells. c-Myc inhibitor 16 iodide is promising for research of breast cancer[1].

Product Specifications

CAS Number

[3061380-62-6]

UNSPSC

12352005

Target

Apoptosis; c-Myc

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

CC[N+]1=C(/C=C/C2=CC=C(OCC3=CC=CC=C3)C=C2)C=CC4=CC=CC=C41.[I-]

Molecular Formula

C26H24INO

Molecular Weight

493.38

References & Citations

[1]Wang X, et al. Design and synthesis of novel styrylquinolinium derivatives for the treatment of breast Cancer: Targeting the c-Myc G-quadruplex. Eur J Med Chem. 2025 Jul 5;291:117663.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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