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Rapaglutin A

Rapaglutin A is a glucose transporter (GLUT) inhibitor. Rapaglutin A is a pan-GLUT inhibitor of Class I isoforms GLUT1, GLUT3, and GLUT4 with an IC50 of 12 nM. Rapaglutin A has an inhibitory effect on A549 proliferation[1].

Product Specifications

Product Name Alternative

RgA; JW11-D2

UNSPSC

12352005

Target

GLUT

Related Pathways

Membrane Transporter/Ion Channel

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

COC(C=C1CC[C@@H]2C3=CC=CC(NC(CCC(N([C@H](C(N[C@@H](C(N([C@@](C(NCC(N(CC/C=C/C(OCC(C)(C(C(N4[C@](CCCC4)([H])C(O2)=O)=O)=O)C)=O)C)=O)=O)([H])[C@H](C)CC)C)=O)CC5=CC=CC=C5)=O)CC(C)C)C)=O)=O)=C3)=C(C=C1)OC

Molecular Formula

C64H87N7O14

Molecular Weight

1178.41

References & Citations

[1]Marnie Kotlyar, et al. Identification of Rapaglutin E as an Isoform-Specific Inhibitor of Glucose Transporter 1. ACS Chem Biol. 2025 Apr 14.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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