E3 Ligase Ligand-linker Conjugate 183
E3 Ligase Ligand-linker Conjugate 183 is an E3 ligase ligand-linker conjugate of PCSK9 autophagic degrader 2 (HY-176043) . E3 Ligase Ligand-linker Conjugate 183 consists of LC3B ligand 2 (HY-176045) and the corresponding linker (HY-141373) [1].
Product Specifications
CAS Number
[3081572-35-9]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C1N(CCOCCOCCOCCBr)C2=C(C=C(I)C=C2)/C1=C\C3=CC(Br)=C(O)C(Br)=C3
Molecular Formula
C23H23Br3INO5
Molecular Weight
760.05
References & Citations
[1]Hongyu Wu, et al. PCSK9 Targeted Autophagosome-Tethering Compounds: Design, Synthesis, and Antiatherosclerosis Evaluation. J Med Chem. 2025 Apr 24;68 (8) :8190-8207.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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