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LC3B ligand 2

LC3B ligand 2 is a ligand for E3 ubiquitin ligase. LC3B ligand 2 can be connected to the ligand for protein by a linker to form PROTAC PCSK9 autophagic degrader 2. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

Product Specifications

UNSPSC

12352005

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer; Cardiovascular Disease

Smiles

O=C1NC2=C(C=C(I)C=C2)/C1=C\C3=CC(Br)=C(O)C(Br)=C3

Molecular Formula

C15H8Br2INO2

Molecular Weight

520.94

References & Citations

[1]Wu H, et al. PCSK9 Targeted Autophagosome-Tethering Compounds: Design, Synthesis, and Antiatherosclerosis Evaluation. J Med Chem. 2025 Apr 24;68 (8) :8190-8207.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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