MS1262-C3-amide-C10-amine
MS1262-C3-amide-C10-amine is a E3 Ligase Ligand-Linker Conjugate. MS1262-C3-amide-C10-amine incorporates a GLP ligand for the E3 ligase SPOP , and a PROTAC linker (HY-176037). MS1262-C3-amide-C10-amine can be used to design PROTACs such as MS479 (HY-176035).
Product Specifications
UNSPSC
12352211
Target
MAGL; Target Protein Ligand-Linker Conjugates
Related Pathways
Metabolic Enzyme/Protease; PROTAC
Field of Research
Others
Smiles
NCCCCCCCCCCNC(CCCN1CCC(NC2=C3C=C(OC)C(OCCCN4CCCC4)=CC3=NC(N5CCOCC5)=C2)CC1)=O
Molecular Formula
C40H67N7O4
Molecular Weight
710.00
References & Citations
[1]Deng Z, et al., Harnessing the SPOP E3 Ubiquitin Ligase via a Bridged Proteolysis Targeting Chimera (PROTAC) Strategy for Targeted Protein Degradation. J Med Chem. 2025 Apr 24;68 (8) :8634-8647.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC741472-100 1x 100 µL
BRCA1 (Breast Marker) (BRCA1/1472), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details ![Rad51 Recombinant Rabbit Monoclonal Antibody [JM54-26]](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea815df/imageurl/et1705-96.webp)
ET1705-96 100 µL
Rad51 Recombinant Rabbit Monoclonal Antibody [JM54-26]
Sign In for Pricing
View Details 
![IGF2BP1 Mouse Monoclonal Antibody [Clone ID: OTI1F7]](https://cdn.genprice.uk/products/937/68dd18bc061270361e90917b/imageurl/cf815058.webp)
CF815058 100 µg
IGF2BP1 Mouse Monoclonal Antibody [Clone ID: OTI1F7]
Sign In for Pricing
View Details 