MS1262-C3-amide-C10-amine
MS1262-C3-amide-C10-amine is a E3 Ligase Ligand-Linker Conjugate. MS1262-C3-amide-C10-amine incorporates a GLP ligand for the E3 ligase SPOP (HY-176036), and a PROTAC linker (HY-176037) . MS1262-C3-amide-C10-amine can be used to design PROTACs such as MS479 (HY-176035) [1].
Product Specifications
UNSPSC
12352211
Target
MAGL; Target Protein Ligand-Linker Conjugates
Related Pathways
Metabolic Enzyme/Protease; PROTAC
Field of Research
Others
Smiles
NCCCCCCCCCCNC(CCCN1CCC(NC2=C3C=C(OC)C(OCCCN4CCCC4)=CC3=NC(N5CCOCC5)=C2)CC1)=O
Molecular Formula
C40H67N7O4
Molecular Weight
710.00
References & Citations
[1]Deng Z, et al., Harnessing the SPOP E3 Ubiquitin Ligase via a Bridged Proteolysis Targeting Chimera (PROTAC) Strategy for Targeted Protein Degradation. J Med Chem. 2025 Apr 24;68 (8) :8634-8647.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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