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MS1262

MS1262 is a ligand for the E3 enzyme SPOP substrate GLP and can recruit SPOP. MS1262 can be used to synthesize MS479.

Product Specifications

CAS Number

3070323-06-4

UNSPSC

12352005

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

98.61

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

COC1=CC2=C(C=C1OCCCN3CCCC3)N=C(N4CCOCC4)C=C2NC5CCN(C(C)C)CC5

Molecular Formula

C29H45N5O3

Molecular Weight

511.70

References & Citations

[1]Zhijie Deng, et al. Harnessing the SPOP E3 Ubiquitin Ligase via a Bridged Proteolysis Targeting Chimera (PROTAC) Strategy for Targeted Protein Degradation. J Med Chem. 2025 Apr 24;68 (8) :8634-8647.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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