MS1262
MS1262 is a ligand for the E3 enzyme SPOP substrate GLP and can recruit SPOP. MS1262 can be used to synthesize MS479 (HY-176035) [1].
Product Specifications
CAS Number
[3070323-06-4]
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.61
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=CC2=C(C=C1OCCCN3CCCC3)N=C(N4CCOCC4)C=C2NC5CCN(C(C)C)CC5
Molecular Formula
C29H45N5O3
Molecular Weight
511.70
References & Citations
[1]Zhijie Deng, et al. Harnessing the SPOP E3 Ubiquitin Ligase via a Bridged Proteolysis Targeting Chimera (PROTAC) Strategy for Targeted Protein Degradation. J Med Chem. 2025 Apr 24;68 (8) :8634-8647.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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