CP-LC-1422

CP-LC-1422 is a homocysteine-derived ionizable amino lipid with high RNA delivery capability and can mediate high-level protein expression in vivo. CP-LC-1422 exhibits significant spleen targeting via intravenous injection in a lipid nanoparticle (LNP) formulation with no significant toxicity observed[1].

Product Specifications

UNSPSC

12352211

Target

Liposome

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Smiles

O=C(C(NC(CCCCC(SCCC(OCCCCCC(C)C)=O)CCSCCC(OCCCCCC(C)C)=O)=O)CCSCCC(OCCCCCCCC(C)C)=O)NCCN(C)C

Molecular Formula

C51H97N3O8S3

Molecular Weight

976.53

References & Citations

[1]Jörgensen AM, et al. Biodegradable Cationic and Ionizable Cationic Lipids: A Roadmap for Safer Pharmaceutical Excipients. Small. 2023 Apr;19 (17) :e2206968.