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IP receptor agonist 1

IP receptor agonist 1 (compound 6c-14S) is an orally active IP receptor agonist, with an IC50 of 0.15 μM for inhibiting platelet aggregation induced by ADP in rabbit platelet-rich plasma. IP receptor agonist 1 can be used for study of Pulmonary arterial hypertension[1].

Product Specifications

CAS Number

3029113-61-6

UNSPSC

12352005

Target

Prostaglandin Receptor

Related Pathways

GPCR/G Protein

Field of Research

Inflammation/Immunology

Smiles

CC1(CN(CC[C@@H]1OCC(O)=O)C2=CN=C(C3=CC=CC=C3)C(C4=CC=CC=C4)=N2)C

Molecular Formula

C25H27N3O3

Molecular Weight

417.50

References & Citations

[1]Cai X, et al. Synthesis and Evaluation of Diphenylpyrazine Cyclic Amine Derivatives as IP Receptor Agonists. ACS Med Chem Lett. 2025 Aug 21;16 (9) :1772-1779.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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