IP receptor agonist 1
IP receptor agonist 1 (compound 6c-14S) is an orally active IP receptor agonist, with an IC50 of 0.15 μM for inhibiting platelet aggregation induced by ADP (HY-W010918,300 μM) in rabbit platelet-rich plasma. IP receptor agonist 1 can be used for study of Pulmonary arterial hypertension[1].
Product Specifications
CAS Number
[3029113-61-6]
UNSPSC
12352005
Target
Prostaglandin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Smiles
CC1(CN(CC[C@@H]1OCC(O)=O)C2=CN=C(C3=CC=CC=C3)C(C4=CC=CC=C4)=N2)C
Molecular Formula
C25H27N3O3
Molecular Weight
417.50
References & Citations
[1]Cai X, et al. Synthesis and Evaluation of Diphenylpyrazine Cyclic Amine Derivatives as IP Receptor Agonists. ACS Med Chem Lett. 2025 Aug 21;16 (9) :1772-1779.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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