HAT-IN-9
HAT-IN-9 (Compound 3F) is a selective proliferation inhibitor targeting Trypanosoma brucei. HAT-IN-9 inhibits the proliferation and division of Trypanosoma brucei. HAT-IN-9 is promising for research of African trypanosomiasis (HAT, i.e., sleeping sickness) [1].
Product Specifications
UNSPSC
12352005
Target
Parasite
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
FC(F)(F)C1=C(C=CC(NC2=NC=NC3=CC=C(C=C23)C4=CC=CC(N5CCOCC5)=C4)=C1)[N+]([O-])=O
Molecular Formula
C25H20F3N5O3
Molecular Weight
495.45
References & Citations
[1]Spijkers-Shaw S, et al. Optimization of Quinazolines for Inhibition of Trypanosoma brucei Proliferation. ACS Med Chem Lett. 2025 Aug 22;16 (9) :1806-1813.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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