Akt3 ligand-1
Akt3 ligand-1 is an Akt3 inhibitor (IC50 = 0.1 nM) and a ligand for the target protein for PROTAC (Akt3). Akt3 ligand-1 can be used to synthesize PROTAC Akt3 Degrader-1.
Product Specifications
CAS Number
2794098-49-8
UNSPSC
12352005
Target
Akt; Ligands for Target Protein for PROTAC
Related Pathways
PI3K/Akt/mTOR; PROTAC
Field of Research
Cancer
Smiles
O=C1NC2=NC=NC(N3[C@H]4C[C@H]4N(CC3)C([C@@H](C5=CC=C(C=C5)Cl)CN)=O)=C2[C@@H](C1)C
Molecular Formula
C22H25ClN6O2
Molecular Weight
440.93
References & Citations
[1]Wu YB, et al. Design, Synthesis, and Biological Evaluation of Isoform-Selective Akt3 Degraders. J Med Chem. 2025 Sep 11;68 (17) :18272-18288.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Akt3
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC400630-500 1x 500 µL
Mucin 1 / EMA / Episialin / CD227 (VU-2G7), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040096-500 1x 500 µL
Histone H1 (AE-4), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400158-100 1x 100 µL
Cytokeratin 17 (E3), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC881820-500 1x 500 µL
Ep-CAM / CD326 (Epithelial Marker) (rVU-1D9), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040178-100 1x 100 µL
CD50 (ICAM-3) (186-2G9), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details