MLS000099089
MLS000099089 is a 12/15-lipoxygenase (12/15-LOX) inhibitor with IC50 values of 3.4 μM and 10 μM for human and mice 12/15-LOX, respectively. MLS000099089 displays higher selectivity for 12/15-LOX over 5-LOX and COX-2. MLS000099089 can be used for the study of stroke[1].
Product Specifications
CAS Number
[423735-70-0]
UNSPSC
12352005
Target
Lipoxygenase
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
OC1=C(C2=NNC(C3=C(C)C=CC=C3)=C2)C=C(C)C=C1
Molecular Formula
C17H16N2O
Molecular Weight
264.32
References & Citations
[1]Armstrong MM, et al. A potent and selective inhibitor targeting human and murine 12/15-LOX. Bioorg Med Chem. 2016 Mar 15;24 (6) :1183-90.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
12-LOX;15-LOX
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