TUB-010 drug-linker

TUB-010 drug-linker is a drug-linker conjugate for ADC, which comprises a mitotic inhibitor MMAE (HY-15162) and a linker. TUB-010 drug-linker can be used for synthesis of ADC TUB-010[1].

Product Specifications

UNSPSC

12352005

Target

Drug-Linker Conjugates for ADC

Related Pathways

Antibody-drug Conjugate/ADC Related

Field of Research

Cancer

Smiles

O=C(O)[C@@H](NC)CC1=CC=C(O)C(/C=N/OCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N3CCC[C@H]3[C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C4=CC=CC=C4)=O)=O)C)=O)=O)=O)C=C2)=O)=O)=O)=C1

Molecular Formula

C71H108N12O17

Molecular Weight

1401.69

References & Citations

[1]Gerlach M, et al. TUB-010, a novel anti-CD30 antibody-drug conjugate based on Tub-tag technology, widens the therapeutic window by reducing toxicity while maintaining high efficacy. Mol Cancer Ther. 2025 Aug 20.