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FEN1-IN-8

FEN1-IN-8 (compund 15) is a selective FEN1 inhibitor, with IC50 values of FEN1 and 100 nM to 1 μM for EXO1, respectively. FEN1-IN-8 can be used for study of colorectal cancer and gastric cancer[1].

Product Specifications

CAS Number

3098173-31-7

UNSPSC

12352005

Target

FLAP

Related Pathways

Immunology/Inflammation

Field of Research

Cancer

Smiles

ClC1=C2C=CC=CC2=CC=C1[C@H](C)OC3=NN(C[C@@H](COCC4)N4C5=O)C5=C(O)C3=O

Molecular Formula

C22H20ClN3O5

Molecular Weight

441.86

References & Citations

[1]Lars Burgdorf, et al. Compounds modulating flap endonuclease (fen1) . WO2025172706A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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