FEN1-IN-8
FEN1-IN-8 (compund 15) is a selective FEN1 inhibitor, with IC50 values of FEN1 and 100 nM to 1 μM for EXO1, respectively. FEN1-IN-8 can be used for study of colorectal cancer and gastric cancer[1].
Product Specifications
CAS Number
[3098173-31-7]
UNSPSC
12352005
Target
FLAP
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Smiles
ClC1=C2C=CC=CC2=CC=C1[C@H](C)OC3=NN(C[C@@H](COCC4)N4C5=O)C5=C(O)C3=O
Molecular Formula
C22H20ClN3O5
Molecular Weight
441.86
References & Citations
[1]Lars Burgdorf, et al. Compounds modulating flap endonuclease (fen1) . WO2025172706A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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