EMD-C02602
EMD-C02602 is a GCN2-targeting agent with IC50 values of 0.023 μM, 4.52 μM, > 10 μM and 0.048 μM for GCN2, PERK, HRland PKR, respectively[1].
Product Specifications
UNSPSC
12352005
Target
Eukaryotic Initiation Factor (eIF)
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=S(NC[C@@H]1CN(C2=NC=NC(C3=CN=C4C=CC(C(F)F)=NN43)=C2)C[C@H](C)C1(F)F)(C)=O
Molecular Formula
C19H21F4N7O2S
Molecular Weight
487.47
References & Citations
[1]Tameire F, et al. In Vivo Tumor Growth Control by General Control Nonderepressible 2-Targeting Agents Results from Kinase Activation. Mol Cancer Ther. 2025 Sep 5:OF1-OF13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported