RAPT-37-Me

RAPT-37-Me is a GCN2-targeting agent with IC50 values of 0.002μM, > 10 μM,4.40 μM and 1.31 μM for GCN2, PERK, HRl and PKR, respectively[1].

Product Specifications

CAS Number

[2396467-34-6]

UNSPSC

12352005

Target

Eukaryotic Initiation Factor (eIF)

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

O=C(NC)[C@@]1(C)C[C@H](NC2=NC=C(C3=N2)C(Br)=NN3C(C=C4F)=CC5=C4N=CC=C5)CC1

Molecular Formula

C22H21BrFN7O

Molecular Weight

498.35

References & Citations

[1]Tameire F, et al. In Vivo Tumor Growth Control by General Control Nonderepressible 2-Targeting Agents Results from Kinase Activation. Mol Cancer Ther. 2025 Sep 5:OF1-OF13.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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