(Rac) -NSD2-PWWP1-IN-4
(Rac) -NSD2-PWWP1-IN-4 (compound 7) is an effective NSD2-PWWP1 inhibitor IC50 and Kd values are 0.21 and 0.15 μM. (Rac) -NSD2-PWWP1-IN-4 can be used in tumor research[1].
Product Specifications
UNSPSC
12352005
Target
Histone Methyltransferase
Related Pathways
Epigenetics
Field of Research
Cancer
Smiles
O=C(N)NCC1N(C2=NC(C)=CC(N(CC)CC3=CC=NC=C3)=N2)CCC1
Molecular Formula
C19H27N7O
Molecular Weight
369.46
References & Citations
[1]Collie GW, et al. Structural and Molecular Insight into the PWWP1 Domain of NSD2 from the Discovery of Novel Binders Via DNA-Encoded Library Screening. ACS Med Chem Lett. 2025 Aug 25;16 (9) :1703-1708.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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