(Rac) -NSD2-PWWP1-IN-4

(Rac) -NSD2-PWWP1-IN-4 (compound 7) is an effective NSD2-PWWP1 inhibitor IC50 and Kd values are 0.21 and 0.15 μM. (Rac) -NSD2-PWWP1-IN-4 can be used in tumor research[1].

Product Specifications

UNSPSC

12352005

Target

Histone Methyltransferase

Related Pathways

Epigenetics

Field of Research

Cancer

Smiles

O=C(N)NCC1N(C2=NC(C)=CC(N(CC)CC3=CC=NC=C3)=N2)CCC1

Molecular Formula

C19H27N7O

Molecular Weight

369.46

References & Citations

[1]Collie GW, et al. Structural and Molecular Insight into the PWWP1 Domain of NSD2 from the Discovery of Novel Binders Via DNA-Encoded Library Screening. ACS Med Chem Lett. 2025 Aug 25;16 (9) :1703-1708.