Aldose reductase-IN-9

Aldose reductase-IN-9 (Compound 8b) is an Aldose reductase (ALR2) inhibitor with a Ki value of 3.59 nM. Aldose reductase-IN-9 has anti-tumor activity[1].

Product Specifications

UNSPSC

12352005

Target

Aldose Reductase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

O=C1/C(CCC2=C1C=CC=C2)=C/C3=CC4=C(C=C3)N(CCCCCC)C5=C4C=CC=C5

Molecular Formula

C29H29NO

Molecular Weight

407.55

References & Citations

[1]Güleç Ö, et al. Chalcone-inspired indole, carbazole, and phenothiazine hybrids as potent aldose reductase inhibitors with selective anticancer potential: Rational design, synthesis, and multi-level characterization. Bioorg Chem. 2025 Sep;164:108861.