HCA-I/hCA-II-IN-2
HCA-I/ HCA-II-IN-2 (compound 5 k) is an effective inhibitor of human carbonic anhydrase I (hCA-I) and II (hCA-II) . The IC50 for hCA I and hCA II are 89.25 and 54.50 nM respectively[1].
Product Specifications
UNSPSC
12352005
Target
Carbonic Anhydrase
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=S(C1=CC=C(C2=CC=CC=C2)C=C1)(OC3=C(/C=N/NC(NC4=CC=CC=C4F)=S)C=CC=C3OCC)=O
Molecular Formula
C28H24FN3O4S2
Molecular Weight
549.64
References & Citations
[1]Rafiq A, et al. Synthesis, human carbonic anhydrase I and II inhibition, and in silico studies of 2-ethoxy-6-formylphenyl [1,1'-biphenyl]-4-sulfonate derived thiosemicarbazones. Bioorg Chem. 2025 Sep;164:108836.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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