TQFL13
TQFL13 is derivative of Thymoquinone (TQ) with potent anti-breast cancer activity. TQFL13 exhibits higher cytotoxicity against breast cancer cells (BT549, MDA-MB-231, 4T1). TQFL13 increases apoptosis and blocks the cell cycle at S and G2/G1 phases in breast cancer cells. TQFL13 shows dose-dependent anti-tumor efficacy in mouse breast cancer allograft model. TQFL13 can be used for the study of breast cancer[1].
Product Specifications
CAS Number
2822560-46-1
UNSPSC
12352005
Target
Apoptosis; Drug Derivative
Related Pathways
Apoptosis; Others
Field of Research
Cancer
Smiles
COC1=CC=C(C(OC)=C1OC)/C=N/C2=C(C(C=C(C2=O)C(C)C)=O)C
Molecular Formula
C20H23NO5
Molecular Weight
357.40
References & Citations
[1]Wei C, et al. TQFL13, a novel synthetic derivative of thymoquinone (TQ), is more capable of inhibiting breast cancer progression than TQ. Bioorg Chem. 2025 Sep;164:108837.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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