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TAU-IN-5

TAU-IN-5 (compound 13) is a TAU protein inhibitor with an EC50 of 0.81 μM. TAU-IN-5 inhibits the formation of tau (2N4R isoform) oligomers and reduces the formation of tau dimers. TAU-IN-5 can be used in the study of Alzheimer's disease (AD) and Parkinson's disease (PD) [1].

Product Specifications

UNSPSC

12352005

Target

Tau Protein

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Smiles

O=C(C(C1=O)=CC2=C(O1)C=CC=C2)NC3=CC=C(O)C(O)=C3

Molecular Formula

C16H11NO5

Molecular Weight

297.26

References & Citations

[1]Ademoye TA, et al. In Vitro Evaluation of Amide-Linked Coumarin Scaffolds for the Inhibition of α‑Synuclein and Tau Aggregation. ACS Omega. 2025 Aug 18;10 (34) :38498-38514.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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