TAU-IN-5
TAU-IN-5 (compound 13) is a TAU protein inhibitor with an EC50 of 0.81 μM. TAU-IN-5 inhibits the formation of tau (2N4R isoform) oligomers and reduces the formation of tau dimers. TAU-IN-5 can be used in the study of Alzheimer's disease (AD) and Parkinson's disease (PD) [1].
Product Specifications
UNSPSC
12352005
Target
Tau Protein
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(C(C1=O)=CC2=C(O1)C=CC=C2)NC3=CC=C(O)C(O)=C3
Molecular Formula
C16H11NO5
Molecular Weight
297.26
References & Citations
[1]Ademoye TA, et al. In Vitro Evaluation of Amide-Linked Coumarin Scaffolds for the Inhibition of α‑Synuclein and Tau Aggregation. ACS Omega. 2025 Aug 18;10 (34) :38498-38514.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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