MK-5108-NH-PEG2-alkyne
MK-5108-NH-PEG2-alkyne is a Aurora kinase A (AURKA) inhibitor. MK-5108-NH-PEG2-alkyne can be used for synthesis of PROTAC AURKA degrader 1 (HY-175830) [1].
Product Specifications
UNSPSC
12352005
Target
Aurora Kinase; Ligands for Target Protein for PROTAC
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; PROTAC
Field of Research
Cancer
Smiles
FC(C(Cl)=CC=C1)=C1OC(CC2)CCC2(C(NCCOCCOCC#C)=O)CC3=CC=CC(NC4=NC=CS4)=N3
Molecular Formula
C29H32ClFN4O4S
Molecular Weight
587.11
References & Citations
[1]Mitrovic M, et al. Click. Screen. Degrade. A Miniaturized D2B Workflow for rapid PROTAC Discovery[J]. bioRxiv, 2025: 2025.07. 29.667383.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Aurora A
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
