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PpGalNAc-T2-IN-1

PpGalNAc-T2-IN-1 (Compound 15) is a Polypeptide N-acetyl-galactosaminyltransferase 2 (ppGalNAc-T2) inhibitor with an IC50 of 7.11 μM. ppGalNAc-T2-IN-1 can be used for metabolic and neurodevelopmental disorders research[1].

Product Specifications

CAS Number

[1112431-86-3]

UNSPSC

12352005

Target

Others

Related Pathways

Others

Field of Research

Metabolic Disease; Neurological Disease

Smiles

N#CC1=C(SCCN2C(C3=C(C2=O)C=CC=C3)=O)N=C(C4=CC=CC=C4)C=C1

Molecular Formula

C22H15N3O2S

Molecular Weight

385.44

References & Citations

[1]Shi D, et al. Discovery of small-molecule modulators of ppGalNAc-T2 targeting the metastable states during its loop-closing process. Bioorg Med Chem Lett. 2025 Aug 16;129:130373.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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