SMU-V18
SMU-V18 is a vesicular stomatitis virus (VSV) inhibitor, with an EC50 of 6.2 μM. SMU-V18 inhibits VSV-GFP fluorescence intensity, viral mRNA/protein expression, and progeny virus replication. SMU-V18 interferes with early viral infection stages, also effective against wild-type VSV (VSV-WT) . SMU-V18 inhibits VSV-GFP in mouse tissues and prolongs survival. SMU-V18 can be used for the study of vesicular stomatitis virus (VSV) infection[1].
Product Specifications
UNSPSC
12352005
Target
VSV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(C1=NC(C2=CC=C3OCCOC3=C2)=NC=C1)NC4=CC(F)=C(F)C(F)=C4
Molecular Formula
C19H12F3N3O3
Molecular Weight
387.31
References & Citations
[1]Ren Z, et al. Design, synthesis, and biological evaluation of novel pyrimidine/pyridine derivatives for Vesicular Stomatitis Virus (VSV) infection. Eur J Med Chem. 2025 Dec 5;299:118051.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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