Z55660043
Z55660043 is a Regulator of G protein signaling-14 (RGS14) inhibitor with an IC50 of 2.3 μM. Z55660043 selectively and non-covalently inhibits RGS14 GTPase-accelerating protein (GAP) activity without measurable cytotoxicity. Z55660043 can be used for central nervous system and metabolic disorders research[1].
Product Specifications
CAS Number
[865271-09-6]
UNSPSC
12352005
Target
RGS Protein
Related Pathways
GPCR/G Protein
Field of Research
Metabolic Disease; Neurological Disease
Smiles
COC1=CC=C(C=C1)OCC2=NN=C3SC=C(NN23)C4=CC(OC)=C(C=C4)OC
Molecular Formula
C20H20N4O4S
Molecular Weight
412.46
References & Citations
[1]Agogo-Mawuli PS, et al. Developing inhibitors of the guanosine triphosphate hydrolysis accelerating activity of Regulator of G protein Signaling-14. bioRxiv [Preprint]. 2025 Aug 9:2025.06.11.659181.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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