Riboswit-modulator-1
Riboswit-modulator-1 (Compound A1), a covalent RNA ligand, is a bacterial Flavin mononucleotide (FMN) riboswitch modulator. Riboswit-modulator-1 modifies unpaired guanine residues (G11 and G62) proximal to the FMN-binding site through a proximity-driven mechanism, and interferes with its conformational transitions. Riboswit-modulator-1 acts as a negative antagonist by eliciting the opposite effect of the natural effector molecule[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
CC1=CC2=C(N=C(C(N3)=O)C(N2CCNC4=CC=C(C(C(O)O)=O)C=C4)=NC3=O)C=C1C
Molecular Formula
C22H21N5O5
Molecular Weight
435.43
References & Citations
[1]Li C, et al. Structure-Guided Design of a Bioactive Covalent Small Molecule Targeting a Riboswitch. bioRxiv [Preprint]. 2025 Aug 2:2025.08.01.668122.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
A2295-15A2 100 µg
Annexin I, CT (Annexin-1, ANX 1, ANX1, Annexin A1, ANXA 1, ANXA1, Calpactin II, Calpactin-2, Chromobindin 9, Lipocortin I, LPC 1, LPC1, p35, Phospholipase A2 Inhibitory Protein) discontinued
Ask
View Details ![MLH1 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1C1]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
TA805066BM 100 µL
MLH1 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1C1]
Ask
View Details MBS1387814-01 0.02 mg (E-Coli)
Recombinant Mouse Ras-related protein Rab-3B (Rab3b)
Ask
View Details