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CYP1B1-IN-11

CYP1B1-IN-11 (Compound M2) is a selective CYP1B1 inhibitor with an IC50 of 0.00605 pM. CYP1B1-IN-11 effectively reverses DMBA -induced Paclitaxel (HY-B0015) resistance and CYP1B1-IN-11 suppresses tumor cells invasion and migration. CYP1B1-IN-11 can be used for tumor drug resistance research[1].

Product Specifications

UNSPSC

12352005

Target

Cytochrome P450

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

CNC1=C2C=CC=CC2=NC(/C=C/C3=C(OC)C=CC=C3F)=N1.Cl

Molecular Formula

C18H17ClFN3O

Molecular Weight

345.80

References & Citations

[1]Cai J, et al. trans-Styrylquinazolinone CYP1B1 inhibitors as potential therapeutics in A549 cells. Eur J Med Chem. 2025 Nov 15;298:118000.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CYP1

Frequently Asked Questions

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