CYP1B1-IN-11
CYP1B1-IN-11 (Compound M2) is a selective CYP1B1 inhibitor with an IC50 of 0.00605 pM. CYP1B1-IN-11 effectively reverses DMBA (HY-W011845) -induced Paclitaxel (HY-B0015) resistance and CYP1B1-IN-11 suppresses tumor cells invasion and migration. CYP1B1-IN-11 can be used for tumor drug resistance research[1].
Product Specifications
UNSPSC
12352005
Target
Cytochrome P450
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CNC1=C2C=CC=CC2=NC(/C=C/C3=C(OC)C=CC=C3F)=N1.Cl
Molecular Formula
C18H17ClFN3O
Molecular Weight
345.80
References & Citations
[1]Cai J, et al. trans-Styrylquinazolinone CYP1B1 inhibitors as potential therapeutics in A549 cells. Eur J Med Chem. 2025 Nov 15;298:118000.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CYP1
Curated Selection
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