Ac-BIM-acid (bromide)
Ac-BIM-acid bromide is a derivative of Acridine. Ac-BIM-acid bromide significantly inhibits amyloid fibrillation. Ac-BIM-acid bromide modulates the structure of N-terminal region of Saccharomyces cerevisiae Stm1 protein (Stm1_N1-113) and the amyloid morphology of human Aβ42 protein, inhibiting theirs growth. Ac-BIM-acid bromide can be used for Alzheimer’s disease research[1].
Product Specifications
UNSPSC
12352005
Target
Amyloid-β
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
O=C(C[N+]1=CN(CC2=CC=CC3=CC4=CC=CC(CN5C=[N+](CC(O)=O)C6=CC=CC=C56)=C4N=C23)C7=CC=CC=C71)O.[Br-].[Br-]
Molecular Formula
C33H27Br2N5O4
Molecular Weight
717.41
References & Citations
[1]Uttamrao P P, et al. Modulation of Saccharomyces cerevisiae Stm1_N1-113 and human AB42 amyloid fibril morphology by 3, 3'- (acridine-4, 5-diylbis (methylene) ) bis (1- (carboxymethyl) -1H-benzimidazolium) dibromide[J]. bioRxiv, 2025: 2025.08. 04.668593.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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