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C3TD078

C3TD078 is a WDR5 WIN site inhibitor with a Ki of 0.03 nM. C3TD078 has potent antiproliferative activity and reduces the stem-cell frequency of cancer stem cells (CSCs) . C3TD078 can be used for glioblastoma (GBM) research[1].

Product Specifications

UNSPSC

12352005

Target

WDR5

Related Pathways

Epigenetics

Field of Research

Cancer

Smiles

FC(C1=NN(C)C=C1C2=CC(CN3C=CN=C3C)=CC4=C2CCC5=C4N=NN5CC6=CC(OC)=CC(OC)=C6)(F)F

Molecular Formula

C29H28F3N7O2

Molecular Weight

563.57

References & Citations

[1]Coker J A, et al. Development and Characterization of Triazole-Based WDR5 Inhibitors for the Treatment of Glioblastoma[J]. bioRxiv, 2025: 2025.07. 29.667410.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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