Afi-FSP1-1
Afi-FSP1-1 is a Ferroptosis suppressor protein 1 (FSP1) inhibitor with an Ki of 0.283 μM. afi-FSP1-1 has a superior binding capacity to FSP1-FAD-NAD+. afi-FSP1-1 can induces ferroptosis in cancer cells. afi-FSP1-1 can be used for cancers research[1].
Product Specifications
CAS Number
[3072951-35-7]
UNSPSC
12352005
Target
Ferroptosis
Related Pathways
Apoptosis
Field of Research
Cancer
Smiles
CC1(OCCC2=C1C=CC(C(N3CCC(CC3)C4=NC(C5=CC=CC=C5)=NN4)=O)=C2)C
Molecular Formula
C25H28N4O2
Molecular Weight
416.52
References & Citations
[1]Gorgulla C, et al. AI-Enhanced Adaptive Virtual Screening Platform Enabling Exploration of 69 Billion Molecules Discovers Structurally Validated FSP1 Inhibitors[J]. bioRxiv, 2023: 2023.04. 25.537981.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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