α-synuclein-IN-16

α-synuclein-IN-16 (Compound H1) is a α-synuclein inhibitor. α-synuclein-IN-16 significantly inhibits the secondary nucleation in α-synuclein aggregation. α-synuclein-IN-16 can be used for Parkinson’s disease research[1].

Product Specifications

UNSPSC

12352005

Target

α-synuclein

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Smiles

C[C@@H]1CC(C2=C3C(C4=C([C@@H]([C@@]3([C@@H]([C@@H]5OC([C@H]6CCCN6[C@@]25C1)=O)O)O)O)C(O)=CC=C4)=O)=O

Molecular Formula

C24H25NO8

Molecular Weight

455.46

References & Citations

[1]Zhang H, et al. Structure-based Generation of a Secondary Nucleation Inhibitor in alpha-Synuclein Aggregation Using a Conditional Diffusion Model[J]. bioRxiv, 2025: 2025.08. 16.670694.