MBL-IN-6
MBL-IN-6 (Compound 6d) is a Metallo-β-lactamase (MBL) inhibitor with Kis of 2.6 and 0.08 μM for NDM-1 and VIM-2, respectively. MBL-IN-6 has a synergistic activities with Imipenem (HY-B1369A) on MBL-producing clinical isolates (such as E. coli SI-M001, K. pneumonia T2301 and S. marcescens SI-1591) with MICs of 2-64 μg/mL. MBL-IN-6 does not have off-target effects without ACE-1 inhibition activity. MBL-IN-6 can be used for antimicrobial resistance research[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial; Beta-lactamase
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(N)[C@@H]1N(C2=CC=CC=C2C1(CC)CC)C([C@@H](CS)C)=O
Molecular Formula
C17H24N2O2S
Molecular Weight
320.45
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-175724/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Bovine Endoplasmic reticulum resident protein 29, ERP29 ELISA Kit
Bovine Endoplasmic reticulum resident protein 29, ERP29 ELISA Kit
Bovine Endoplasmic reticulum resident protein 29, ERP29 ELISA Kit
Bovine Endoplasmic reticulum resident protein 29, ERP29 ELISA Kit
