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JSZ16

JSZ16 is a Succinate dehydrogenase (SDH) inhibitor with an IC50 of 30.3 μM. JSZ16 has potent broad-spectrum fungicidal activity, such as Sclerotinia sclerotiorum, Botrytis cinerea and Colletotrichum fragariae, with an EC50 of 4.4 mg/L for Sclerotinia sclerotiorum. JSZ16 influences the cell membrane permeability of pathogenic fungi. JSZ16 can be used for the development of fungicide[1].

Product Specifications

UNSPSC

12352005

Target

Fungal

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C(N1CCCCC1)CC2=CC=C3N=C(SC3=C2)SC4=CC=C(C=C4)Cl

Molecular Formula

C20H19ClN2OS2

Molecular Weight

402.96

References & Citations

[1]Huang D, et al. Design of Novel Benzothiazole-Based Succinate Dehydrogenase Inhibitors Inspired by Polyrhachis dives: Structural Optimization, Potential Fungicidal Activity, and Mechanistic Insights. J Agric Food Chem. 2025 Aug 27;73 (34) :21317-21329.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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