AKT1-IN-10
AKT1-IN-10 (Compound I-118) is a non-covalent allosteric AKT1 inhibitor with an IC50 of [1].
Product Specifications
CAS Number
[3077847-90-3]
UNSPSC
12352005
Target
Akt
Related Pathways
PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
CC1=C(C=CC(NC([C@@H]2CC[C@H](CC2)C(O)=O)=O)=N1)N3C4=NC(C5=CC=CC=C5)=CC=C4N=C3C6=C(N=CC=C6)N
Molecular Formula
C31H29N7O3
Molecular Weight
547.61
References & Citations
[1]Maria Jesus Blanco-Pillado, et, al, Substituted aminopyridine compounds for use as akt1 inhibitors, WO2025059577A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Akt1
Curated Selection
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