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6- (2,4-Dioxopyrimidin-1-yl) -1-methylindole

6- (2,4-Dioxopyrimidin-1-yl) -1-methylindole is an E3 ligase ligand used in the synthesis of the PROTAC Androgen receptor degrader-1.

Product Specifications

CAS Number

2766178-76-9

UNSPSC

12352100

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

CN1C=CC2=CC=C(N3C(NC(CC3)=O)=O)C=C12

Molecular Formula

C13H13N3O2

Molecular Weight

243.26

References & Citations

[1]Peter Astles, et al. Bifunctional compounds capable of degrading androgen receptors. WO2024189488A1.2024-09-19.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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