6- (2,4-Dioxopyrimidin-1-yl) -1-methylindole
6- (2,4-Dioxopyrimidin-1-yl) -1-methylindole is an E3 ligase ligand used in the synthesis of the PROTAC Androgen receptor degrader-1 (HY-175652) [1].
Product Specifications
CAS Number
[2766178-76-9]
UNSPSC
12352100
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CN1C=CC2=CC=C(N3C(NC(CC3)=O)=O)C=C12
Molecular Formula
C13H13N3O2
Molecular Weight
243.26
References & Citations
[1]Peter Astles, et al. Bifunctional compounds capable of degrading androgen receptors. WO2024189488A1.2024-09-19.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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