PROTAC Androgen receptor degrader-1
PROTAC Androgen receptor degrader-1 (Ex.14) is a PROTAC degrader targeting the androgen receptor with a DC50 of 6 nM. PROTAC Androgen receptor degrader-1 is used in prostate cancer research. (Structure Note: Pink: target protein ligand ; Blue: E3 ligase ligand (HY-175654) ; Black: linker).
Product Specifications
CAS Number
3056515-10-4
UNSPSC
12352100
Target
Androgen Receptor; PROTACs
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.15
Smiles
N#CC1=NNC2=C(N3C[C@H](C4=CC=C(N5CCC(CC5)CN6CCC(C7=CC8=CC=C(N9C(NC(CC9)=O)=O)C=C8N7C)CC6)C=C4)CCC3)C=CC(Cl)=C12
Molecular Formula
C43H48ClN9O2
Molecular Weight
758.35
References & Citations
[1]Peter Astles, et al. Bifunctional compounds capable of degrading androgen receptors. WO2024189488A1.2024-09-19.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![Peroxiredoxin 6 (PRDX6) Mouse Monoclonal Antibody [Clone ID: OTI4D1]](https://cdn.genprice.uk/products/937/68dd18bb061270361e908f80/imageurl/cf813653.webp)
Peroxiredoxin 6 (PRDX6) Mouse Monoclonal Antibody [Clone ID: OTI4D1]
CD61 / Integrin 3 / Platelet Glycoprotein IIIa (Platelet Marker) (ITGB3/2145), Biotin conjugate, 0.1mg/mL
Thyroglobulin (Thyroidal Cell Marker) (TGB/1970R), Biotin conjugate, 0.1mg/mL
