LRRK2-IN-20
LRRK2-IN-20 (EX. 4.64) is a LRRK2 inhibitor with a pIC50 of 0.7921 nM. LRRK2-IN-20 can be used in Parkinson's disease (PD) research[1].
Product Specifications
CAS Number
[2763594-19-8]
UNSPSC
12352100
Target
LRRK2
Related Pathways
Autophagy
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
ClC1=C(N2CCN(C3(COC3)C)CC2)C=C4N=C(NC5=CN(CC(C)(C)C)N=C5)N=CC4=C1
Molecular Formula
C24H32ClN7O
Molecular Weight
470.01
References & Citations
[1]John J. Acton J, et al. 2-aminoquinazolines as lrrk2 inhibitors, pharmaceutical compositions, and uses thereof. WO2022051337A1.2022-03-10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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