Myosin-5-IN-2
Myosin-5-IN-2 (Compound G19) is a Myosin-5 inhibitor. Myosin-5-IN-2 has an antifungal activity against Fusarium graminearum (Fg), Botrytis cinerea and Rhizoctonia solani with an EC50s of 0.326 μg/mL for Fg. Myosin-5-IN-2 has effective protective and curative control efficiency for wheat leaves. Myosin-5-IN-2 severely damages the surface integrity of mycelial cells and induces cytoplasmic leakage. Myosin-5-IN-2 can be used for fungal infections like fusarium head blight (FHB) research[1].
Product Specifications
UNSPSC
12352100
Target
Fungal; Myosin
Related Pathways
Anti-infection; Cytoskeleton
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C(OCC)/C(C#N)=C(NC(C1=CC=CO1)=O)/C2=CC=CC=C2
Molecular Formula
C17H14N2O4
Molecular Weight
310.30
References & Citations
[1]Hou ST, et al. Synthesis and Antifungal Activity Evaluation of Novel 2-Cyanoacrylate Derivatives Containing Arylamide Moiety as Potential Myosin-5 Inhibitors. J Agric Food Chem. 2025 Aug 20;73 (33) :20664-20674.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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