G-418 (disulfate) (Standard)

G-418 (disulfate) (Standard) is the analytical standard of G-418 (disulfate) . This product is intended for research and analytical applications. G-418 disulfate (Geneticin sulfate), is an aminoglycoside antibiotic, inhibits protein synthesis in eukaryotes and prokaryotes. G-418 disulfate is commonly used as a selective agent for eukaryotic cells[1].

Product Specifications

CAS Number

[108321-42-2]

Product Name Alternative

Geneticin sulfate (Standard) ; Antibiotic G-418 sulfate (Standard)

UNSPSC

12352005

Target

Antibiotic; Bacterial; Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Infection

Purity

95.22

Smiles

O=S(O)(O)=O.O[C@@H]([C@@H]1O[C@@]([C@@H]([C@@H](O)[C@@H]2O)N)([H])O[C@]2([H])[C@H](O)C)[C@H]([C@@H](C[C@@H]1N)N)O[C@](OC[C@](C)(O)[C@@H]3NC)([H])[C@@H]3O.O=S(O)(O)=O

Molecular Formula

C20H44N4O18S2

Molecular Weight

692.71

References & Citations

[1]Giordano-Santini R, et al. An antibiotic selection marker for nematode transgenesis. Nat Methods. 2010;7 (9) :721-723.|[2]Volarevic M, et al. A novel G418 conjugate results in targeted selection of genetically protected hepatocytes without bystander toxicity. Bioconjug Chem. 2007;18 (6) :1965-1971.|[3]Kwon KM, et al. Disialyl GD2 ganglioside suppresses ICAM-1-mediated invasiveness in human breast cancer MDA-MB231 cells. Int J Biol Sci. 2017;13 (3) :265-275. Published 2017 Feb 12.|[4]Davies J, et al. A new selective agent for eukaryotic cloning vectors. Am J Trop Med Hyg. 1980;29 (5 Suppl) :1089-1092.