DOTA-ALB-02
DOTA-ALB-02 is an albumin-bound FAP inhibitor (FAPI) ligand. DOTA-ALB-02 labeled with 177Lu has a high FAP-binding affinity and enhanced tumor uptake and retention with a significant tumor/nontarget ratio. DOTA-ALB-02 can be used for PET/CT and SPECT/CT imaging of cancers, especially late-stage cancers[1].
Product Specifications
UNSPSC
12352100
Target
FAP
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Smiles
O=C(NCCCCC(C(NC1=CC=CC2=C1N=CC=C2C(NCC(N3CC(C[C@H]3C#N)(F)F)=O)=O)=O)NC(CCCC4=CC=C(I)C=C4)=O)CCOCCOCCOCCOCCOCCOCCNC(CN5CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC5)=O
Molecular Formula
C64H91F2IN12O18
Molecular Weight
1481.38
References & Citations
[1]Wu T, et al. Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites. Mol Cancer Ther. 2025 Aug 1;24 (8) :1186-1196.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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