FLT3/JAK2/BRD4 ligand-1
FLT3/JAK2/BRD4 ligand-1 is a FLT3/JAK2/BRD4 ligand. FLT3/JAK2/BRD4 ligand-1 can be used for synthesis PROTAC FLT3/JAK2/BRD4 Degrader-1.
Product Specifications
CAS Number
3067695-60-4
UNSPSC
12352100
Target
Epigenetic Reader Domain; FLT3; JAK; Ligands for Target Protein for PROTAC
Related Pathways
Epigenetics; JAK/STAT Signaling; PROTAC; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
CC1=C(N=C(N=C1)NC2=CC=C(C(F)=C2)N3CCNCC3)NC4=CC=CC(NS(C(C)(C)C)(=O)=O)=C4
Molecular Formula
C25H32FN7O2S
Molecular Weight
513.63
References & Citations
[1]Xiang Q, et al. Discovery of Potent Dual PROTAC Degraders Targeting BET-Kinase To Overcome FLT3 Inhibitor Resistance. J Med Chem. 2025 Aug 28;68 (16) :17303-17322.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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