AChE/nAChR-IN-1
AChE/nAChR-IN-1 (Compound 1a) is dual-functional inhibitor of AChE and nAChR. AChE/nAChR-IN-1 has potent toxicity and larvicidal effectiveness against Culex pipiens larvae with a LC50 of 4 ng/mL. AChE/nAChR-IN-1 can be used as larvicides for mosquito-borne diseases research[1].
Product Specifications
CAS Number
[59417-09-3]
UNSPSC
12352100
Target
Cholinesterase (ChE) ; nAChR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection; Neurological Disease
Smiles
O=C(OC)/C(C1=CC=CC=C1C(O)=O)=C/C2=CC=CS2
Molecular Formula
C15H12O4S
Molecular Weight
288.32
References & Citations
[1]Kamal M, et al. Synthesis and in silico studies of new thiophene-isoquinolinone hybrids as potential larvicides against Culex pipiens. Sci Rep. 2025 Jul 31;15 (1) :28031.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE
Curated Selection
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