TM-04-064-02
TM-04-064-02 is a molecular glue degrader. TM-04-064-02 induces proteins (such as IKZF1/3, PPIL4, ETF1 and PDE6D) to bind to CRBN, promoting their ubiquitination and degradation[1].
Product Specifications
UNSPSC
12352100
Target
IKZF Family; Molecular Glues; Phosphodiesterase (PDE)
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; PROTAC
Field of Research
Others
Smiles
O=C(NCCCCCCCCNC1=CC=CC2=C1C(N(C2=O)C3CCC(NC3=O)=O)=O)CCN4C=NC5=C(N=CN=C54)N
Molecular Formula
C29H35N9O5
Molecular Weight
589.65
References & Citations
[1]Baek K, et al. Unveiling the hidden interactome of CRBN molecular glues. Nat Commun. 2025 Jul 24;16 (1) :6831.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IKZF1; IKZF3; PDE6
Curated Selection
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